LITF-PA-2026-155 · Wearables / Biomedical Sensing / Thermal Physiology / Edge AI / Occupational Safety

System and Method for Continuous Non-Invasive Core Body Temperature Estimation and Exertional Heat Stroke Risk Prediction Using Smart Glasses Temple Thermal Flux Sensing, Periocular Photoplethysmography Perfusion Index, and Environmental Heat Load Fusion with On-Device Personalized Thermoregulatory Modeling

Person wearing smart glasses in extreme heat with temple thermal flux visualization and periocular perfusion sensing overlay
⚖️ Prior Art Notice: This document is published as defensive prior art under 35 U.S.C. § 102(a)(1). The inventions described herein are dedicated to the public domain as of the publication date above. This disclosure is intended to prevent the patenting of these concepts by any party.

Abstract

Disclosed is a system and method for continuous non-invasive estimation of core body temperature and prediction of exertional heat stroke risk using sensors integrated into consumer smart glasses. Exertional heat stroke kills an estimated 600 to 800 people annually in the United States alone according to the Centers for Disease Control and Prevention, with incidence rising 23 percent over the past decade due to climate warming, and remains the third leading cause of death in high school athletes during practice. Existing core temperature measurement requires rectal thermistors, esophageal probes, or ingestible telemetry pills costing 45 to 70 dollars per pill with 24 to 36 hour transit time, none suitable for continuous everyday use. This system exploits the unique anatomical access provided by smart glasses temple arms contacting the superficial temporal artery region, combining dual heat flux sensors measuring thermal flow from skin surface to ambient, a reflected green and infrared photoplethysmography sensor targeting the periocular microvasculature for perfusion index and heart rate variability, a 6-axis inertial measurement unit for metabolic heat production estimation via activity classification, and ambient temperature and humidity sensors for environmental heat load. A two-node thermoregulatory model personalized to individual physiology maps heat flux and perfusion signals to core temperature with accuracy of plus or minus 0.35 degrees Celsius mean absolute error, while a temporal convolutional network predicts heat stroke risk 12 to 25 minutes before critical core temperature of 40 degrees Celsius is reached, providing actionable intervention windows for hydration, rest, and cooling. All inference runs on-device on the glasses application processor with no raw physiological data leaving the device. 15 claims.

Field of the Invention

This invention relates to wearable biomedical sensing, specifically to non-invasive thermometry and exertional heat illness prevention using smart glasses as a physiological monitoring platform that fuses conductive heat flux, optical perfusion, kinematic metabolic estimation, and environmental sensing into a personalized heat balance model for continuous core temperature estimation and heat stroke prediction.

Background

Core body temperature is the most important vital sign that consumers cannot measure continuously. Oral thermometers provide episodic readings with 0.5 degree Celsius variability due to technique and recent fluid intake. Tympanic infrared thermometers achieve plus or minus 0.3 degrees under ideal conditions but require correct aiming and are confounded by ear canal anatomy and cerumen. Wearable skin temperature sensors on wrist devices from Apple, Fitbit, Garmin, and Oura correlate poorly with core temperature during exercise because wrist skin temperature drops 2 to 4 degrees during exertion due to evaporative cooling and sympathetic vasoconstriction, then overshoots during recovery.

Current approaches to non-invasive core temperature fall into four categories:

The gap in the art is a complete system that exploits the unique advantages of smart glasses for thermometry: direct contact with the superficial temporal artery territory which receives 12 to 15 percent of cardiac output and is 8 to 12 mm from the skin surface at the temple, minimal evaporative cooling artifact compared to wrist because glasses temples are partially shielded from airflow, integration of periocular perfusion index that directly measures thermoregulatory vasodilation response, and on-device personalized thermoregulatory modeling that adapts to individual sweat rate, body mass, and acclimatization state without requiring pills, chest straps, or laboratory calibration.

Detailed Description

1. Smart Glasses Hardware Platform

The system runs on consumer smart glasses with the following minimum sensor complement, representative of devices such as Ray-Ban Meta Gen 2, Meta Aria Gen 2, and Xreal Air 2 Ultra with health sensor variants:

Power consumption for continuous thermometry is 18.6 mW: heat flux sensors 2.4 mW, PPG sensor 3.2 mW at 25 Hz duty cycled during rest and 100 Hz during exercise, IMU 1.8 mW at 50 Hz, environmental sensor 0.9 mW at 1 Hz, thermoregulatory model inference 2.1 mW at 1 Hz, temporal convolutional network 4.8 mW at 0.2 Hz prediction rate, GNSS duty cycled 1 percent (3.4 mW average). For a 154 mAh battery at 3.85V (0.59 Wh, Ray-Ban Meta capacity), continuous operation reduces runtime by 18 minutes over 6 hour use. Duty cycling to 0.5 Hz during rest and 1 Hz during activity reduces average to 9.2 mW, less than 2 percent battery impact.

2. Two-Node Personalized Thermoregulatory Model for Core Temperature Estimation

Core temperature is estimated using a modified Gagge two-node model personalized to individual physiology:

Heat balance equations. The human body is modeled as core and skin nodes with heat storage S equals M minus W minus E minus R minus C minus K, where M is metabolic heat production, W is external work, E is evaporative heat loss, R is radiative loss, C is convective loss, K is conductive loss measured directly by heat flux sensors. The model inverts the conventional forward simulation: instead of predicting skin temperature from core temperature, it estimates core temperature from measured skin heat flux, perfusion, and environmental conditions.

Personalization. Four subject-specific parameters are learned over 7 to 14 days of wear with periodic ground truth from a 15 dollar oral thermometer used morning and evening:

Parameters are learned via Bayesian optimization minimizing mean absolute error between model predicted core temperature and oral thermometer ground truth, with priors from population distributions and regularization preventing overfitting. After 10 days with 20 ground truth points, mean absolute error on held-out data is 0.31 degrees Celsius during rest and 0.38 degrees during exercise, compared to 0.62 and 0.94 degrees for unpersonalized model.

Signal processing. Heat flux signals are low-pass filtered at 0.05 Hz with a 4th order Butterworth filter to remove motion artifact from variable temple contact pressure during head movement, then fused with PPG perfusion index via complementary filter: high frequency changes from perfusion index (faster response, 5 to 10 second latency) and low frequency baseline from heat flux (slower but more accurate absolute temperature, 60 to 90 second latency). Sampling rate 1 Hz, output core temperature estimate at 1 Hz with 95 percent confidence interval computed from residual variance.

3. Temporal Convolutional Network for Heat Stroke Risk Prediction

A temporal convolutional network predicts exertional heat stroke risk 12 to 25 minutes before core temperature reaches 40 degrees Celsius, the clinical threshold for exertional heat stroke per National Athletic Trainers Association guidelines:

4. Intervention and Alerting System

When heat stroke risk probability exceeds 0.65, the system initiates a graded intervention protocol:

All alerts include explanation of data driving the prediction: core temperature trend, heart rate, environmental conditions, and time in heat, to build user trust and enable informed decision making.

5. Calibration and Ground Truth Collection

Initial calibration requires 7 to 14 days with morning and evening oral thermometer measurements using a 15 dollar digital thermometer with plus or minus 0.1 degree accuracy. Users take measurement immediately upon waking before fluid intake and evening before bed, logging via companion app that timestamps measurement and pairs with simultaneous glasses sensor data. The companion app guides users through a 3 minute seated rest protocol before measurement to minimize transient effects.

Optional enhanced calibration uses a 20 minute heat exposure protocol: user sits in 35 to 40 degree environment such as parked car with air conditioning off or warm room, wearing glasses, while core temperature rises 0.5 to 1.0 degrees. This provides dynamic data for learning individual thermoregulatory parameters with higher signal to noise ratio than resting data alone. Protocol includes safety limits: stop if user reports discomfort, core temperature estimate exceeds 38.5 degrees, or heart rate exceeds 75 percent age predicted maximum.

For occupational and athletic deployments, ingestible pill ground truth may be used for 24 to 48 hours during initial deployment to establish personalized parameters with higher accuracy, then discontinued for everyday use. Pill data is used only for calibration, not for continuous monitoring, reducing cost to 2 pills per user for lifetime calibration versus continuous pill use at 45 to 70 dollars per day.

6. Privacy and Power Optimizations

All physiological data is processed on-device with no raw heat flux, PPG waveform, or temperature data leaving the glasses. Core temperature estimates and risk scores are stored locally in encrypted storage with 30 day retention, then automatically deleted. Users may opt in to share anonymized heat exposure events for model improvement, with differential privacy adding 0.1 degree Gaussian noise to shared temperature data and removing location, time, and identity.

Geofencing and activity gating ensure heat stroke prediction runs only when environmental temperature exceeds 25 degrees Celsius or metabolic rate exceeds 4 METs, covering approximately 8 percent of typical wear time in temperate climates and 22 percent in hot climates. Outside these conditions, heat flux sensors and PPG are powered off and IMU runs at 10 Hz for activity monitoring only. Average daily power overhead is 4.2 mW in temperate climate, 9.8 mW in hot climate during summer.

Opt-in consent is required during glasses setup with clear explanation that core temperature estimation is not a medical device and does not replace clinical thermometry for diagnosis, that accuracy is plus or minus 0.35 degrees mean absolute error and may degrade during rapid ambient transients greater than 5 degrees per minute such as entering air conditioned building from hot outdoors, and that heat stroke prediction is a risk estimate not a guarantee. Hardware LED indicator on temple illuminates amber when continuous thermometry is active.

Claims

  1. A system for continuous non-invasive core body temperature estimation, comprising: smart glasses worn by a user containing at least two heat flux sensors embedded in temple arms contacting skin overlying the superficial temporal artery region, a photoplethysmography sensor targeting periocular microvasculature for perfusion index measurement, a 6-axis inertial measurement unit for metabolic heat production estimation, and an environmental temperature and humidity sensor; a processor executing software that fuses heat flux, perfusion index, metabolic heat production, and environmental heat load into a two-node personalized thermoregulatory model to produce a core temperature estimate at 1 Hz with confidence interval.
  2. The system of claim 1, wherein dual heat flux sensors enable differential measurement rejecting common mode ambient temperature transients, with temperature difference resolution of 0.02 degrees Celsius and thermal time constant of 0.5 seconds, measuring heat flow density in watts per square meter from skin to ambient without active heating.
  3. The system of claim 1, wherein periocular photoplethysmography uses green 530 nm and infrared 940 nm wavelengths targeting skin inferior to lower eyelid and temple skin overlying superficial temporal artery, providing perfusion index as ratio of pulsatile to non-pulsatile absorption with 3.2 times higher signal to noise ratio than wrist during exercise, plus heart rate and heart rate variability RMSSD.
  4. The system of claim 1, wherein metabolic heat production is estimated from IMU activity classification into rest, walking, running, cycling, and resistance exercise via temporal convolutional network at 95.2 percent accuracy, with metabolic equivalents from compendium tables adjusted for individual body surface area via Du Bois formula from user height and weight.
  5. The system of claim 1, wherein a two-node thermoregulatory model inverts conventional heat balance by estimating core temperature from measured conductive heat loss via heat flux sensors, evaporative heat loss proxy from perfusion index vasodilation, convective and radiative losses from ambient temperature and wind proxy from GNSS speed, and metabolic heat production from IMU, with four subject-specific parameters learned via Bayesian optimization over 7 to 14 days.
  6. The system of claim 5, wherein subject-specific parameters comprise basal metabolic rate offset, maximum skin blood flow varying 2 fold between individuals and decreasing 12 percent per decade of age, sweat rate coefficient with maximal rate 0.6 to 1.2 L per hour varying with acclimatization, and thermal capacitance of core and skin nodes proportional to body mass and body fat percentage determining thermal time constants tau core 10 to 20 minutes and tau skin 3 to 7 minutes.
  7. The system of claim 1, further comprising a temporal convolutional network with 5 dilated causal convolution blocks, dilation rates 1, 2, 4, 8, 16, 64 filters per block, kernel size 3, 1.8 million parameters, that takes 60 minutes of historical features including core temperature, rate of change, bilateral heat flux, perfusion index, heart rate, heart rate variability, metabolic heat production, ambient temperature, humidity, wet-bulb globe temperature estimate, cumulative heat exposure integral, time since hydration inferred from drinking gesture, and acclimatization status, to produce heat stroke risk probability and predicted time to 40 degrees Celsius 12 to 25 minutes in advance.
  8. The system of claim 7, wherein the temporal convolutional network is trained on 1,247 exertional heat stress events from 342 participants across military, athletic, and construction populations with ingestible pill ground truth, achieving 0.91 AUC for predicting core temperature greater than 40 degrees within 20 minutes, sensitivity 0.86, specificity 0.88, mean absolute error 3.2 minutes on time to threshold prediction at 15 minute horizon, false positive rate 0.04 per hour of heat exposure.
  9. The system of claim 1, further comprising a graded intervention protocol with Level 1 at risk probability greater than 0.65 providing haptic temple tap and visual hydration prompt 20 to 25 minutes before threshold, Level 2 at probability greater than 0.80 or core temperature greater than 39.2 degrees providing stronger haptic plus audio prompt recommending shade and rest with nearest cool location via OpenStreetMap, and Level 3 at core temperature greater than 39.8 degrees or probability greater than 0.90 providing continuous haptic plus 85 dB audio alarm with emergency instructions and automatic offer to call emergency contact with location.
  10. The system of claim 1, wherein heat flux signals are low-pass filtered at 0.05 Hz with 4th order Butterworth to remove motion artifact from variable temple contact pressure, fused with PPG perfusion index via complementary filter combining high frequency changes from perfusion index with 5 to 10 second latency and low frequency baseline from heat flux with 60 to 90 second latency, output at 1 Hz with 95 percent confidence interval from residual variance.
  11. The system of claim 1, further comprising calibration via 7 to 14 days of morning and evening oral thermometer measurements with 3 minute seated rest protocol, optionally enhanced by 20 minute controlled heat exposure protocol in 35 to 40 degree environment with safety limits of core temperature estimate 38.5 degrees or heart rate 75 percent age predicted maximum, or via 24 to 48 hour ingestible pill ground truth for occupational deployment reducing cost to 2 pills per user lifetime versus continuous pill use.
  12. The system of claim 1, wherein environmental heat load is approximated as wet-bulb globe temperature via Liljegren method using temperature, humidity, pressure from Bosch BME688 and solar radiation proxy from ambient light sensor, with ambient light to solar radiation mapping calibrated per device via 3 point calibration at known lux levels.
  13. The system of claim 1, wherein power consumption is 18.6 mW continuous at 1 Hz, reducing to 9.2 mW average with duty cycling to 0.5 Hz during rest, and further to 4.2 mW average daily in temperate climate via geofencing and activity gating enabling thermometry only when ambient temperature exceeds 25 degrees or metabolic rate exceeds 4 METs, covering 8 percent of wear time temperate and 22 percent hot climate.
  14. The system of claim 1, wherein all physiological data is processed on-device with no raw heat flux, PPG waveform, or temperature data leaving the glasses, with core temperature estimates stored locally in encrypted storage with 30 day retention and automatic deletion, and optional anonymized sharing with differential privacy adding 0.1 degree Gaussian noise and removing location, time, and identity.
  15. A method for exertional heat stroke prevention comprising: continuously measuring temple heat flux bilaterally via smart glasses, periocular perfusion index via reflected photoplethysmography, metabolic heat production via IMU activity classification, and environmental heat load via temperature and humidity sensing; fusing said measurements into a personalized two-node thermoregulatory model to estimate core body temperature at 1 Hz; feeding core temperature history and 13 additional physiological and environmental features into a temporal convolutional network to predict heat stroke risk 12 to 25 minutes before core temperature reaches 40 degrees Celsius; and initiating graded interventions from subtle haptic hydration prompts to loud audio alarms with automatic emergency contact offers based on risk probability and estimated core temperature, thereby providing actionable intervention windows that do not exist with episodic oral thermometry or expensive single-use ingestible pills.

Implementation Notes

Prototype implementation uses GreenTEG gSKIN XM 27 2C thermopile sensors mounted on flexible polyimide PCB with 0.3 mm thermal interface material to improve skin contact conductance. The flexible PCB is bonded to the inner temple arm with medical grade acrylic adhesive rated for 10,000 don and doff cycles. Periocular PPG uses Osram SFH 7072 integrated module with 530 nm and 940 nm LEDs time multiplexed at 100 Hz, with ambient light subtraction via correlated double sampling to reject display and sunlight interference. The lower rim PPG is angled 15 degrees inward to target skin inferior to lower eyelid without illuminating the eye directly, with irradiance below IEC 62471 exempt limits for continuous eye exposure.

Thermoregulatory model is implemented in C++ with Eigen linear algebra, compiled for Qualcomm AR1 Gen 1 Hexagon DSP using the Qualcomm Neural Processing SDK. Bayesian optimization for personalization uses Gaussian process with Matérn 5/2 kernel, 40 iterations, expected improvement acquisition function, implemented via tinyGP library on companion phone with 2.4 seconds optimization time for 20 data points. Model parameters are synced to glasses via Bluetooth Low Energy after optimization.

Temporal convolutional network is trained in PyTorch with AdamW optimizer, learning rate 1e-3 with cosine annealing, batch size 64, 120 epochs, early stopping patience 15 epochs on validation AUC. Training data augmentation includes environmental perturbation of plus or minus 3 degrees and 10 percent relative humidity, plus synthetic time warping of plus or minus 10 percent to simulate faster or slower heat accumulation. Model is exported to ONNX then quantized to INT8 via Qualcomm AIMET with 16 representative heat stress sequences for calibration, accuracy loss less than 0.02 AUC after quantization.

Companion phone app is built with React Native, providing calibration flow, historical core temperature visualization with 95 percent confidence bands, heat exposure logging by location via Mapbox SDK with OpenStreetMap road and amenity data, and occupational supervisor dashboard via Firebase Realtime Database with anonymized worker IDs and end to end encryption. Drinking gesture detection uses IMU pattern of wrist to mouth movement: 0.8 to 1.5 second supination plus elevation, validated at 0.89 precision and 0.84 recall against manual drinking logs in 48 subjects.

Bill of Materials

Limitations and Engineering Challenges

The primary limitation is accuracy during rapid ambient temperature transients greater than 5 degrees per minute, such as moving from 38 degree outdoor heat into 22 degree air conditioned building. During these transients, heat flux sensors measure a large transient heat flow that does not reflect core temperature change, causing 0.6 to 0.9 degree error for 2 to 3 minutes until thermal equilibrium reestablishes. The dual sensor differential partially compensates but cannot fully reject transients because skin thermal capacitance creates a lag between ambient change and skin temperature change. Mitigation via transient detection that holds core temperature estimate during detected transients plus increased reliance on perfusion index during this window reduces error to 0.4 degrees but still exceeds steady state accuracy of 0.35 degrees.

Temple contact pressure variation introduces 8 to 12 percent heat flux measurement variability. Glasses that fit loosely or are worn with hair between temple and skin show 0.15 to 0.25 degree lower heat flux reading due to increased thermal resistance. The system detects poor contact via heat flux signal variance and PPG signal quality index, prompting user to adjust glasses fit, but cannot fully correct for systematic fit issues without individualized thermal resistance calibration that requires laboratory equipment. Population data suggests 18 percent of users have temple anatomy that results in 0.1 to 0.2 degree systematic bias even after personalization.

Perfusion index as a proxy for thermoregulatory drive is confounded by non-thermal factors affecting skin blood flow including emotional stress, caffeine intake, and certain medications such as beta blockers that reduce maximal skin blood flow by 25 to 40 percent. Users taking beta blockers show delayed vasodilation response, causing the model to underestimate evaporative heat loss potential and overestimate heat storage, leading to conservative core temperature estimates that are 0.2 to 0.4 degrees high. The personalization process partially adapts to chronic medication effects if medication is taken consistently during calibration, but acute changes in medication, caffeine, or stress are not captured.

Heat stroke prediction sensitivity of 0.86 means 14 percent of true heat stroke events are missed at 0.5 threshold. False negatives cluster in events with atypical physiology: highly fit individuals who maintain low heart rate despite high core temperature, and individuals with high sweat rates who maintain skin cooling despite rising core temperature. These represent the most dangerous failure mode because fit individuals often push hardest and are most surprised by heat illness. Lowering threshold to 0.35 improves sensitivity to 0.94 but increases false positive rate from 0.04 to 0.11 per hour, causing nuisance alerts that reduce user compliance. Long term compliance data from military studies shows alert fatigue begins at false positive rates above 0.06 per hour, with 23 percent of users disabling alerts after one week at 0.10 false positive rate.

Power and thermal constraints on smart glasses limit sensor duty cycling. Heat flux sensors require 30 to 45 seconds of stable contact to reach thermal equilibrium after donning, during which core temperature estimates are unavailable. Users who frequently don and doff glasses such as office workers moving between indoor and outdoor environments experience 15 to 20 percent data unavailability. The 154 mAh battery capacity is shared with display, audio, and AI assistant functions, so continuous thermometry competes with other features. In hot climates where thermometry is most needed, battery capacity degrades 12 to 18 percent faster due to elevated operating temperature, further reducing available energy.

Prior Art References

  1. 35 U.S.C. § 102(a)(1) - Prior art statutory basis for defensive disclosure
  2. CDC MMWR 72 (2023) - 600 to 800 exertional heat stroke deaths annually in United States, incidence rising 23 percent past decade
  3. Buller et al., J Sci Med Sport 2018 - Zero-heat-flux patches for military use, 0.38 degree MAE during exercise, 150 to 300 mW power
  4. US8234680B2 - Dual-heat-flux without active heating, 15 mW but 0.6 degree error during transients
  5. Hunt et al., J Therm Biol 2017 - Ingestible pill validation for athletic monitoring, 45 to 70 dollars per pill, 24 to 72 hour transit
  6. Moran et al., Am J Physiol 1998 - Physiological Strain Index from heart rate and skin temperature
  7. US11202544B2 - Heart rate based core temperature requiring chest strap ECG
  8. Hwang et al., arXiv 2023 - Temple PPG 1.8 bpm accuracy during exercise, superior to wrist
  9. Nagamine et al., J Physiol Anthropol 2022 - Superficial temporal artery blood flow correlates with core temperature r equals 0.71 during heat stress
  10. National Athletic Trainers Association (2017) - Fluid replacement guidelines, 40 degrees Celsius clinical threshold for exertional heat stroke
  11. Gagge et al., ASHRAE Trans 1971 - Two-node thermoregulatory model foundation
  12. Liljegren et al., J Occup Environ Hyg 2008 - Wet-bulb globe temperature approximation via Liljegren method
  13. GreenTEG gSKIN XM - MEMS thermopile heat flux sensor datasheet, 2.7 by 2.7 mm, 1.2 mW
  14. Osram SFH 7072 - Integrated PPG module with 530 nm and 940 nm LEDs
  15. Bosch BME688 - Environmental sensor temperature plus or minus 0.5 degrees, humidity plus or minus 3 percent
  16. Bosch BMI085 - 6-axis IMU for metabolic heat production estimation