🧬 Genomics
CRISPR’s Newest Weapon Doesn’t Edit Genes. It Shreds the Genome of Every Cancer Cell It Finds.
Two papers published in Nature within five weeks show that a CRISPR enzyme called Cas12a2 can sense mutant RNA transcripts inside cancer cells and respond by destroying their chromosomes. In mice, a single treatment cut tumor volume in half. The target: mutant p53, the most common genetic alteration in human cancer and one that has defeated every therapeutic approach for 45 years.
